CryoSave: The family stem cell bank.

There are currently over 80 approved therapies where umbilical cord blood stem cells can be used.

CryoSave: The family stem cell bank.

There are currently over 80 approved therapies where umbilical cord blood stem cells can be used.

Over the past 30 years, more than 40,000 cord blood transplants have been performed world-wide.
These transplants have treated blood disorders such as bone marrow failure, haematological malignancies,
inherited blood disorders, immuno-deficiency syndromes and metabolic disorders.

What diseases can currently be treated?

There are currently more than 80 approved therapies, where umbilical cord blood stem cells can be used, for example:

Blood Cancers

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
Chronic Myeloid Leukaemia (CML)
Myelodysplastic Syndrome (MDS)
Multiple Myeloma
Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma

Inherited Metabolic Disorders

Hurler Disease (MPS type IH)
Osteopetrosis
Adrenoleukodystrophy
Krabbe Disease

Bone Marrow Disorders

Aplastic Anaemia,
Unspecified Fanconi Anaemia

More Diseases..

Blood Disorders, Bone Marrow Failure Syndrome, Immunodeficiencies and other diseases like Neuroblastoma and Solid Tumours.

Blood Cancers

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
Chronic Myeloid Leukaemia (CML)
Myelodysplastic Syndrome (MDS)
Multiple Myeloma
Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma

Inherited Metabolic Disorders

Hurler Disease (MPS type IH)
Osteopetrosis
Adrenoleukodystrophy
Krabbe Disease

Bone Marrow Disorders

Aplastic Anaemia,
Unspecified Fanconi Anaemia

More Diseases..

Blood Disorders, Bone Marrow Failure Syndrome, Immunodeficiencies and other diseases like Neuroblastoma and Solid Tumours.

A comprehensive list of current treatable diseases and therapies can be found on Parents’ Guide to Cord Blood.

The future of regenerative therapy
is exciting and ever-advancing.

What clinical trials are in progress?

Clinical trials currently being conducted, are studying the possibility of using cord stem cells in therapies for example:

Acquired hearing loss
Alzheimer’s disease
Acute Ischemic Stroke
Autism Spectrum Disorders
Amyotropic Lateral Sclerosis
Bronchopulmonary dysplasia
Cartilage repair
Critical limb ischemia
Cerebral Palsy
Congenital Diaphragmatic Hernia
Congenital Heart Diseases
Childhood Hearing Loss
Corneal Epithelial Wounds
Ulcerative Colitis / Inflammatory Bowel Disease
Duchenne Muscular Dystrophy
Diabetic Foot Ulcers
Diabetes Mellitus (Type I & Type II)
Diabetes (Type I)
Encephalopathy (neonatal)
Epidermolysis Bullosa
Fertility

Global development delay
Graft versus host diseases
Glaucoma
Hypoplastic left heart syndrome
HIV
Hydrocephalus
Ischemic Stroke (pre/peri-natal)
Intraventricular haemorrhage
Infant Lung Disease
Idiopathic Dilated Cardiomyopathy
In-Utero Brain Injury / Stroke
Liver Cirrhosis
Neurodegenerative Disorders
Preterm Neonatal Complications
Parkinson’s Disease
Rheumatoid Arthritis
Severe Hypoxic-ischemic Encephalopathy
Systemic Lupus Erythematosus
Spinal Cord Injury
Skin-Wound / Burns
Sweat Gland Diseases / Regeneration

References

• Cairo MS, Rocha V, Gluckman E, et al. Alternative allogeneic donor sources for transplantation for childhood diseases: unrelated cord blood and haploidentical family donora. Biol Blood Marrow Transplant. 2008; 14:44-53. • Cairo MS, Tarek N, Lee DA, et al. Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients. Bone Marrow Transplant. 2016;51:27-33.
• Gluckman E, Ruggeri A, Rocha V, et al. for Eurocord, Netcord, World Marrow Donor Association and National Marrow Donor Program. Family-directed umbilical cord blood banking. Haematolgica. 2001; 96: 1700-1707.
• Mazonson P, Kane M, Colberg K, et al. Prevalence of medical conditions potentially amenable to cellular therapy among families privately storing umbilical cord blood. Matern Child Health J. 2016 (online).
•https://clinicaltrials.gov